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Table 3 Associations between expression a of microdomain-forming proteins and clinicopathological characteristics of NSCLC patients

From: Simultaneous expression of flotillin-1, flotillin-2, stomatin and caveolin-1 in non-small cell lung cancer and soft tissue sarcomas

 

Stomatin

Flotillin-1

Flotillin-2

Caveolin-1

 

up

equal

down

up

equal

down

up

equal

down

equal

down

Stomatin

           

up

4

          

equal

 

4

         

down

  

33

        

p

           

Flotillin-1

         

up

3

0

12

18

       

equal

1

1

4

 

10

      

down

0

2

14

  

17

     

p

0,242

        

Flotillin-2

      

up

3

2

15

11

7

5

24

    

equal

0

2

9

4

2

5

 

13

   

down

0

0

6

1

1

5

  

8

  

p

0,39

0,176

     

Caveolin-1

           

equal

1

1

6

5

3

1

4

6

1

12

 

down

3

3

26

13

6

16

19

7

7

 

36

p

0,925

0,155

0,107

  

Tumor size

           

T1-T2

4

1

20

12

7

10

12

11

5

11

20

T3-T4

0

3

13

6

3

7

12

2

3

1

16

p

0,094

0,816

0,117

0,036 b

Lymph node status

           

N0

3

4

12

7

3

9

9

8

1

5

15

N+

1

0

21

11

7

8

15

5

7

7

21

p

0,026 c

0,476

0,078

1

Clinical stage

           

I-II

3

2

18

10

4

11

11

9

3

8

18

III-IV

1

2

15

8

6

6

13

4

5

4

18

p

0,714

0,459

0,277

0,505

Degree of differentiation

           

moderate

3

4

22

10

8

11

17

11

2

10

22

low

1

0

11

8

2

6

7

2

7

2

14

p

0,377

0,432

0,007 c

0,289

  1. aup – higher gene expression in tumors compared with normal tissue samples.
  2. down – lower gene expression in tumors compared with normal tissue samples.
  3. equal – no significant difference in gene expression in tumors versus normal tissue samples.
  4. bFisher’s exact test.
  5. cχ2 test.
  6. Data in bold represents statistically significant values.
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BMC Cancer

ISSN: 1471-2407

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